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GENERAL INFORMATION:

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Manufacturer: Novo Nordisk
Substance: Somatropin (rDNA origin)
Package: 1 Cartridge (15mg/1.5mL)

Common Names

Jintropin, Jintropine, Norditropin, Somatropin, SimpleXx, Hygetropin, Humatrope, Norditropin, Nutropin, Saizen, Biotropin, Zorbtive, Ansomone, Ansomon, Tev-Tropin, Zomacton, Glotropin, Kefei, Kigtropin, Riptropin, Taitropin.

Drug Description

Transparent oily solution.

Norditropin SimpleXx Composition

1 cartridge contains:
Active substance: Human Growth Hormone 10 mg

Bodybuilding Benefits

Human growth hormone in synthetic form used by athletes in periods before contests because of the low detection risk. It offers gains in muscular mass and has the ability to burn fat. It also increases bone density and energy levels thus making  the immune system stronger.

Therapeutic Indication

Is considered an ideal drug in battle against aging and is used in surgical operations, as well as for growth hormone treatment and in case of traumas, severe burns, organ transplantations and cancers, promoting protein combination.

Dosage (Men)

4 to 6 IU per day.

Dosage (Women)

2 IU per day.

Active Life

Varies by injection method.

Norditropin SimpleXx Side Effects

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Much as it is low in side effects, it can provoke some headache, nausea, vomiting and edema of ankles, painful joints, baby naps, carpal tunnel syndrome, water retention, morning aches, acromegal and hypoglycemia.

 Package Presentation

Comes in 30 IU cartridge (10 mg / 1.5 mL).

Storage

Keep cold (+2-+8°C). Protect from light. Keep out of reach of children.

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Idiopathic short stature (ISS) is one of the most controversial indications for GH as pediatric endocrinologists do not agree on its definition, diagnostic criteria, or limits.  In the late 1990s, the pharmaceutical manufacturer Eli Lilly and Company sponsored trials of Humatrope (their brand of rHGH) in children with extreme ISS, those at least 2.25 standard deviations below mean (in the lowest 1.2 percent of the population).  Controversy has arisen as to whether all of these children were truly “short normal” children, since the average IGF1 was low. Most of all, it was not surprising that approval for this extreme degree of shortness led to an increase in the number of parents seeking treatment to make otherwise healthy children a little taller.

ADVERSE EFFECTS

The New England Journal of Medicine published two editorials in 2003 expressing concern about off-label uses of HGH and the proliferation of advertisements for “HGH-Releasing” dietary supplements, and emphasized that there is no evidence that the  use of HGH in healthy adults or in geriatric patients is safe and effective – and as a result emphasized that risks of long-term HGH treatment are unknown. One editorial was by Jeffrey M. Drazen, M.D., the editor-in-chief of the journal; the other one was by Dr. Mary Lee Vance, who provided the NEJM’s editorial original, cautious comment on a much cited 1990 study on the use of HGH in geriatric patients with low growth hormone levels.

GH treatment usually decreases insulin sensitivity, but some studies showed no evidence for increased diabetes incidence in GH-treated adult hypopituitary patients.

a large study recently concluded that “With relatively short follow-up, the overall primary cancer risk in 6840 patients receiving GH as adults was not increased.

Elevated SIRs (which is risk of getting cancer) were found for subgroups in the USA cohort defined by age <35 years or childhood onset GH deficiency

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